Enables Rational PIC™ Design
Xanthos is the platform’s design engine. Starting with a protein target sequence, we determine 3D structures, predict ligand binding, generate linkers, predict ternary complexes and refine PIC™ selection through several layers of filters including molecular dynamics and QSAR.
From Data to Hit
Automated Synthesis Lab
Hephaistos is the platform’s synthesis engine. Machine learning-driven retrosynthesis and a robotized synthesis lab create real-world, custom chemical matter for testing in our automated biology lab (Hades). Our facility includes all necessary organic synthesis equipment, such as fume hoods, evaporators, HPLC, LC-MS and microfluidic synthesis.
From Hit to Compound
Hades is the platform’s biological information engine. It generates experimental data obtained from our automated lab which we began constructing mid 2021. We exploit several, different biochemical assays and phenotypic screening protocols, and have in-house capabilities in cell culture, high-content imaging, functional assays and molecular biology.
From Compound to Lead
The PIC™ Engineering Company
We are CelerisTx
We are an international team of highly skilled experts from disciplines as computational chemistry, medicinal chemistry, biology and machine learning.
Our team is complemented by highly esteemed advisors and investors at the intersection of artificial intelligence and life sciences.
One Team. One Vision.
CEO, President and Co-Founder
CFO/COO, Director and Co-Founder
Dr. Chris Tame
VP, Head of Drug Discovery and London Office
BOARD OF DIRECTORS
Dr. James Field
Dr. Peter Ho
Observer and Advisor
Dr. Ronjon Nag
Observer and Advisor
Dr. Mark Whittaker
Former SVP Head of Protein Homeostasis at Evotec
Prof. Dr. Jean-Louis Reymond
Former Dir. of Chemistry and Biochemistry at the University of Bern.
Assoc.-Prof. Dr. Johannes Kirchmair
Head of Comp. Drug Discovery and Design at the University of Vienna.
Prof. Dr. Ola Spjuth
Professor at the University of Uppsala.
Prof. Dr. Stefan Knapp
Professor at the Goethe University Frankfurt.